Doing a google search the only reference to 128k and 256 K cluster size was when using NT 4.0.
I reread your post, I' guessing your C drive is =< 8 K cluster size. My first para is why it should be
For you operating system/program partition - 4K cluster size is the best choice. Reason, a large percentage of the files will be =< than 4 K (probably about half will be less than 8K). This means that any file that is 4 K or smalled will still eat up 64 K (ie 500 files @ 4 K or less = 2 Megs while using with 64 K that would be 32 Megs - A big waste with no performance gain.
64K, or larger Cluster size is only recommended for Large file size such as large Jpegs/bitmap pictures and for storing Large video files (ie dot Vob's are typically up to 1 Gig and Blu-ray video files are => 13 gigs. Not sure what the max cluster size is for NTFS. Note, you lose file compression. I'm not sure of the performance gains between a 64K cluster size and say a 128 K cluster size due to the reduction of the file allocation table, might not be that great.
To verify, run a dos prompt. Cd directory to C:\ (ie do a CD.. until you get there) then do a dir *.* /s >filelist.txt.
Load this file into a spread sheet and sort on file size.
Myself, I just wrote a quick program to scan the file and count the number of files less than 4 K, => than 8K but Less than 16K ect