Problem easily solved with an air compressor. Just have to make sure to have the PSI turned down a notch. Have never had problems with sticking dust. Though, I keep my computer room ventilated with an air purifier and don't smoke. Those of you complaining about the caked on dust... it has to be smoke or like... grease from cooking. Normal dust wont "stick" enough to prevent air blow off.
As for the card, this thing is impressive. If it performs as noted then it is upgrade worthy. A couple of these in crossfire would do wonders, and help to keep the noise down.