swap things out and see what happens. be ready to have all the stuff on hand though, registration keys, passwords, usernames, emails, etc... major change in hardware will cause many software to cough up a few parts and not allow you to use them until situation is resolved through the given software registration. normally easy peasy, but still one most go through it.
driver conflicts might be an issue, some software might install certain things for certain hardware vs another, larger games for example.
swap the drive in and run stuff to see if the hardware is working, and then setup a time to format and reinstall. stage it out vs all at once.
to note it, you might come into some issues if for example microsoft windows, and...