Possibly. The issue is that with high core count processors, with hyperthreading as well, there are already issues with thermal controls and managing temps. When you add an on package GPU into the mix, especially a high end one, it may be that there are insurmountable thermal issues resulting.
Ryzen is fairly low TDP though so there may be some room for this addition. Haven't heard anything regarding chips in the works for this though and the fact is that most people wanting a flagship CPU like that are also going to want the power of a discreet card, not something that is barely capable of low to medium settings in most AAA games.