How does an SSD and an HDD work together?

CeeTeePee

Commendable
Oct 24, 2016
1
0
1,510
I have a an SSD as my boot drive and an HDD as my storage. If I have, let's say, Microsoft word on my SSD (but not on my HDD) but my .docx file is on my HDD, will the file still run if I attempted to access it through my HDD?