So I was just wondering, How many Anti-Virus Programs should I have open and working at once for best security? My CPU can handle multi-tasking very well, My PC specs: Core i5 4590, 16 GB RAM, Radeon RX 570 8 GB, I got Malware-Bytes and Avast working Right now, and thinking of getting more Anti-viruses like McAffe and Norton, Please quick answer for my question.