Personally I have never had a GPU fail on me (I have owned many), however I don't tinker with clocks and I buy high quality PSU's/Motherboards and tend to avoid brands that the prevailing wisdom claims are more likely to fail. I have seen statistics that report failure rates of between 1% and 4% however these don't discuss if that is:
A) Failure in QA before going to a customer
B) Failure within warranty
C) Failure based on returns to the AIB partner
The reason all that matters is that it probably hides cards that have failed but the customer just bought another and binned the old card. I can't really give you a figure for how much that actually matters but I think most people get a useful lifespan out of the cards and are ready for...