I looked at the CPU support for that and it doesn't even support the fastest Pentium 4 Xeons. It seems to stop at 533 fsb. Not even 667 or 1066 which the Dempsey Xeons used. That may only support 32 bit CPUs? I've had a couple P4 motherboards that would run 65nm Core 2 Extremes quite well so it's a good question. It has an SiS chipset. Haven't heard of them in a long time.
finally the web site of the manufacturer confirms all of these previous details
LGA775 socket for latest Intel Pentium 4 / Celeron D processor
Supports Hyper-Threading Technology CPU
and final nail in the coffin on the subject the manufacturer has a lovely list of CPUS you can use on this motherboard