Dosflores :
If my e-mail and its 2FA gets hacked, the only security that is compromised is that e-mail account (since I have several different ones, each with its own password and 2FA) and any service I use that e-mail account for. If "the last password you'll ever need" and its 2FA gets hacked, every service you use is compromised.
If you use the same device for 2FA for every account (most people), then it would seem that if your email and 2FA device are compromised then the attacker effectively has access to most of your accounts (given that most accounts allow a password reset via email).