How to turbo-charge your Raspberry Pi 5 with an NVMe boot drive

I understand Downloading the OS to the NVMe board.. But I don't know how you INstall it to the drive when it's attached as a non-boot drive via USB3 and you've already booted from the MicroSD that Has RaspberryPi installed...

If you download it to the NVMe and take care to do everything to prepare it to boot form the NVMe... when you reboot, with the MicroSD removed, won't it just go through the install procedure at that point on the NVMe drive?