It depends.
If placed upright and you live in an earthquake-prone area, then I'd say no. Too unstable.
If placed on its side with rubber feet or no-slip pads, and there are no earthquakes where you live, and it's a low-traffic area so nobody is likely to knock it off, then I'd say go for it.
If the ground in the room tends to be dusty, the up on a dresser might actually be better than on the floor.