Yes you can.. but you can make absolutely sure the RAM is compatible visiting the motherboard manufacturer's product page > Support > Memory Compatibility, which lists RAM brands with speeds and voltages the motherboard supports. You can install any 1333 or 1600 MHz stic of RAM as long as it runs at the voltage that the motherboard supports... for example, most motherboards support 1.5 volt RAM modules, some support 1.65 Volt RAM, and some support 1.35 volt RAM... but if the motherboard BIOS has the options to adjust the voltage to the RAM voltage, it should work without issues but it's better to use RAM with the voltage the motherboard suports by default and avoid the hassle. Another possible issue is some motherboards (very few) don't run well with single channel RAM (single RAM module), and some don't even run... so it's better to use two modules which even work better since dual channel memory works better than single channel.