First - please stay out of the registry. Registry edits are a last resort and only attempted when all data, etc. has been backed up.
Second - update your post to include full system hardware specs and OS.
What make and model CD/DVD drive is installed?
What error messages or pop-up Windows etc., do you see when the failures occur?
Look in Reliability History - there may be an error code or warning therein that corresponds to your driver installation attempts.