If you are surprised that the combination would actually be supported then go around saying you wouldn't do that, you are basically admitting that the compatibility might be mostly moot - hypothetically there but not recommended.
Since AMD has written that making chiplets work on AM4 was an engineering challenge, I'll take it as meaning that AM4 forced AMD to make some performance and power compromises that it wouldn't have needed to on a socket designed from the ground up with chiplets in mind.
Personally, I haven't bothered upgrading CPUs in my own PCs in over 20 years. By the time I run into a CPU or RAM capacity bottleneck, I need new everything else anyway and I'd rather have two years socket cycles if that means not saddling the platform with unnecessary compatibility luggage and engineering compromises.