Also with regard to graphics cards any vague estimate of when we might realize the benefits of pcie4? Is it far enough in the future that it totally doesn't bear any relevance?
While it's impossible to say for sure, it will probably be a number of years. The highest-end graphics cards have only recently begun to show a measurable performance impact from running on a PCIe 2.0 x16 connection, despite PCIe 3.0 having been available on mainstream systems since 2012. And with a mid-range graphics card, you still wouldn't see any meaningful hit to performance from running it in a 2.0 x16 slot. Since 3.0 offers double the bandwidth, I think we can safely assume that the added bandwidth of 4.0 probably won't be relevant to graphics cards for some years to come, even at the high-end, unless something were to drastically change with the design of graphics cards. I suspect that other parts of the system would be holding back performance more than the PCIe connection by that point.
For storage, as has been said, even if a PCIe 4.0 SSD can technically push higher sequential numbers, the real-world performance benefits are likely to be quite minimal in most scenarios. As far as game load times are concerned, fast NVMe SSDs tend to only be around 10% faster at loading today's games compared to SATA SSDs, despite technically being capable of providing multiple times the performance, so the additional benefits of a 4.0 drive seem questionable at this time. A lot of this comes down to the fact that the system is not just loading the data off the drive, but also processing that data in various ways, so the drive itself often isn't what's limiting performance. I wouldn't necessarily say that will always be the case though. Current games are designed with hard drives in mind, but as SSDs become the norm in systems and consoles, we may start to see games designed in ways that make better use of their higher transfer rates. Again, the near-term benefits of PCIe 4.0 are likely to be minimal though, so I wouldn't hold off on buying a system just for that.
One thing I might point out though, is that Intel may be increasing thread counts with next-year's processors, to be more competitive with what AMD is currently offering in terms of multithreaded performance. Rumors suggest that they may be enabling SMT (Hyperthreading) across their lineup for their 10th-gen Core desktop processors, whereas only i9s feature it in their current generation, with the i7s trading it for two more cores compared to the prior gen. If that happens, the next i7s should perform similar to the current i9s, the next i5s like the current i7s, and the next i3s like the current i5s, much like what we saw when Coffee Lake launched two years ago. So, it could potentially be worth waiting for that if you want to go the Intel route, even if PCIe 4.0 probably isn't going to be a big selling point.