I had interrupt problems on Nov 18/2012 and they came back again today Jan 17/2013. My computer worked fine for 2 months by deleting the PIO Mode 1st primary entry, today the interrupts were as high as 89% of CPU, I deleted the 1st primary and 1st secondary entries and then rebooted, my computer thought I had a new disc drive and installed it for me, I then rebooted again and have interrupts 1.5% or less.