Great question. I personally have it right now. It's a great case for it's price and the thermals here are excellent.
Supports 3 Hdd slots, about 2x 2.5 Sata SSDs and overall you can easily fit the largest graphics cards here. The front has a mesh filter and its kept my case clean so far.
Just 1 pet peeve. This case is not the best water cooling supported case. You can practically only fit up to a 240mm Radiator. I know the site says 280, but I have 0 idea where they got that from.
And I know the thermals will be great in this case as we have a similar setup. I have a Ryzen 5 5600X and a 3060ti. I'm using a fully air-cooled setup with a Hyper 212 Turbo. I've put in 4x 120mm NZXT Aer F fans. 2x Front intake. 2x Exhaust. 1 at the rear and 1 on top. The thermals I have here are around 60C - 70C on a heavy gaming session with an ambient temp of around 25C. And well let's be real, the main reason we chose this case was not only for looks but its affordability. Its noise is also quite respectable, though barely audible. It's nothing too loud, but the mesh grill in the front will make itself known. Give or take around 30 - 40 dB from my experience. You'd only really hear it's noise at a silent night, but it is nonetheless there. Dust is also not an issue with this case as the front mesh does a very good job in keeping that out. I've used this for a year, there's barely any dust. You'd have to grab a wet wipe to properly see it.
Another thing is, the cable management. I have to say, it is probably one of the easiest cases I've ever cable managed. I personally have 2 hard drives and 1 SSD in the back. I have no trouble getting the cables to go neatly without much problem closing the back panel. The HDD cage can be adjusted so that you have enough room for your cables. Just one challenge is the 24 Pin cable. I would recommend a sleeve NON-FLAT 24-pin cable, as a flat cable can be more challenging to fit into the plastic cable cage that it has in the back.
Once you get the H510 Flow, I suggest purchasing an additional 120mm fan. Since out of the box it has two. Having an additional 120mm to fill the front grill is very beneficial to thermals. You can also move the exhaust fan to the front, it has a very long PWM cable so it won't be a problem to reach your fan controllers. Though I would not recommend getting the NZXT Aer F, not because it's not good per say, it is quite good. But because it's overpriced. Try the Arctic P12. Much more reasonably priced with about the same performance.
I might edit this post later on to show you all this in photos. Anyways for now, cheers, and I hope you like the H510.