The 5.25" bay has largely been phased out on many of the newest and top performers as these are being used less and less often. It may make sense to, at some point, move to an external enclosure with your optical drive. You may find that you really don't use it as often as you think; I moved my BD-R to an external enclosure and I rarely use it, much to my surprise.
I'm a fan of tempered glass on the cable side. At least then you know the case doesn't have one of those horrid cable-side cases that you need to have four arms to align to get on properly. I've been inside computers for 35 of my 42 years and I still hate those types of panels with a passion.