A good way to look at it is to have the same number of fan slots on your radiators (per side) as you do components. So you've got 4 fan spots and 4 components so you're good. The flow rate is so high that staggering components and cpus isn't a big deal. Definitely put your cpu first since that will dump the least heat into your coolant. One pump would probably be fine for what you have. Especially if you get one of the DDC pumps. Those are higher pressure pumps than the D5. You could even add the EK performance top (or just buy it with it already on) to get a little extra "umph". Hope that helps!