Here is the cpu support list for your motherboard:
www.asus.com
Your I3-6100 has 4 processing threads and a passmark rating of about 4169.
That is when all 4 threads are fully busy.
The single thread performance rating is 2235.
The strongest upgrade would be a I7-7700K.
It has 8 threads and a rating of 9689/2745.
For gaming and overall quickness, the single thread performance is most important.
Run the cpu-Z bench test. Your 6100 should score about 417:
http://valid.x86.fr/bench/tzinb8
The 7700K will be about 500.
You would also want a stronger cooler than the stock 6100 cooler.
It is an easy upgrade, but not a really big boost unless your workload is batch production.
Without budget issues, look to an upgrade to 12th gen.
A simple i3-12100 will have 8 threads and a rating of 13848/ 3533.
It will be noticeably quicker and comes with a cooler.
You will need a lga1700 motherboard and likely a DDR4 B660 motherboard.
add 16gb of ddr4 ram and the upgrade would cost you perhaps$500.
If you do not now have a ssd for windows, that would be my very first upgrade,