There is latency with this Bluetooth Mouse. I didn't notice it so much with the Microsoft Wireless 5000 bluetooth mouse, but occasionally notice it with the MS Presenter 8000 mouse, but only rarely, and that is when i have a lot of tabs open (45+ tabs) or CPU intensive. The advantages of the presenter mouse however out-way this minor disadvantage, but that's personal opinion. This is a great mouse, and lag/latency is almost non-existent, i've noticed various users of this mouse don't experience any latency anyway.