mouse freezes randomly

[Ladythorne]

While in use, mouse will randomly freeze, causing me to unplug/replug it. This does not always work. I have a wireless usb and a wired usb mouse, both of which work on other machines and do it on my Lenovo ThinkCentre M78. (Windows 7). Nothing new has been added or done and the problem is getting progressively worse. Device Manager does not show any issues with either mouse and there are no drivers for either mouse

 

[trapper]

Have you tried different USB ports? Or is it always the same port.