I have had this desk and at least 3 different mice with no problems. The one I am currently using worked just fine 20 mins ago. Now it wont work only on the spot of my desk I use the mouse. I can use the arm of my chair, my clothes, even other areas on the desk. I have tried cleaning the desk seemed to actually worsen the problem I have tired "dirtying" the area and still to no avail. Seriously what is going on here lol