Update your post to include full system hardware specs and OS information.
What PSU did you buy: make, model, wattage, truly new (versus used or refurbished)?
Drives: make, model, capacity, how full?
Look in Reliability History and Event Viewer for error codes, etc. that correspond with the times of "blue pixel glitches".
Have you tried swapping in known working video cables. Likewise tried another known working monitor?
Objective being to determine if the problem follows the cable or monitor or stays with your pc.
Try running the built in Windows Troubleshooters. The troubleshooters may find and fix something.
Corrupted Windows files are another possibility:l try "sfd /scannow" and "dism".
References:
https://www.lifewire.com/how-to-use-sfc-scannow-to-repair-windows-system-files-2626161
https://www.windowscentral.com/how-use-dism-command-line-utility-repair-windows-10-image
As for drivers - did you manually download the drivers via the applicable manufacturer's websites? Then reinstall and reconfigure as applicable doing so yourself?
No third party installers so you have control of the installation.