Question New Motherboard in old HP computer case

Feb 28, 2019
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I have an old Workstation HP xw4400 which I would like to update.
Before buying the wrong nessesary parts, I'd like to know from somebody with potentially corresponding experience, if it is possible, to build in et al a newer ATX Motherboard, because housing and Mainboards are known to be very proprietary and specific in some (older) HP Computers.
Thanks a lot for any advice