The mice are PS2. So the adapter should be converting it to use a USB port. If the adapter isn't working, that doesn't mean the PS2 port is dead. It just means you need to get a different adapter. Or that maybe the mouse is broken.
The keyboard is USB. As long as your keyboard is working, you know that port works. You can get a new adapter, or a new mouse, and use that port to test with.
You can get a PS2 keyboard, and see if that works in your PS2 port. Or, you could get a USB to PS2 adapter, to test your current keyboard on that port.
There are ways to test this, without just assuming you have a dead port. If neither the mouse or the keyboard work on that PS2 port, we're back to my original assumption, that it's a BIOS setting.