I too encountered a similar problem when I upgraded my Dell Precision T7400's 256MB NVIDIA Quadro FX570 card to an EVGA 2GB (GDDR5) GeForceGT730 card. After deleting the old card's drivers, installing the new card and its corresponding drivers, my computer had switched to HDMI audio and the onboard audio wasn't even showing up in the sound control panels as a selectable option. Checking for updates, allowing Windows to attempt to repair the problem, and reinstalling RealTek's audio drivers didn't remedy the lack of sound. What did work (as mentioned previously) was adjusting a BIOS setting. On this particular computer, pressing F2 during startup opens up the BIOS settings menus. Using the arrow keys, I navigated down to "Onboard Devices" and from the sub-menu selected "Integrated Audio". There are three settings from which to choose from. This computer's default setting is "Auto". The other two settings are "On" and "Off". Apparently, my new card's ability to use HDMI causes the "Auto" selection to default to HDMI. Since I'm using an analog audio jack connected to external Logitech speakers, I need the computer's onboard audio enabled. Switching the Integrated Audio from "Auto" to "On" bypasses the whole auto-detection snafu, and will allow one's computer to boot up and detect devices plugged into its on board analog ports. Just be sure to save the new setting when exiting BIOS. All is good now.