What motherboard is this? If it's an intel board, get the latest INF. You might just need to install the drivers before it will recognize the device, therefore windows update won't help.
Also, check the BIOS to make sure that Legacy USB is on, and that all the options are turned on relating to USB.
One more thing, is the usb stick formatted as UDF?
Sorry have to guess since you don't have that much info yet. We'll keep trying.