PC Lock-up, Infinite Sound Loop

[carlwaterman]

I've been searching around for a fix for this and I can't find one that works anywhere, I was wondering if anyone here had any ideas.

For the last few days my PC, when playing games or watching videos, and sometimes when restarting, will often crash, usually within 10-20 minutes of starting the game or video. It completely freezes where it is with the last millisecond of audio looping in a loud buzzing sound for around 30 seconds before it goes silent. To get the PC working again it requires a hard reset. I don't get a BSOD or any sort of error.

Up until now I've tried:

• An old GPU in case it was a GPU error
  Removing all overclocks
  Unplugging all non-essential items from the PSU, such as harddrives other than my OS drive, fans, LEDs, fan controllers etc in case it was a PSU problem
  Disabling audio in the BIOS as I have read that realtek sound chips can cause this problem
  Uninstalling all audio drivers and devices
  Reseating CPU and heatsink as this problem was caused on an old laptop because of the CPU overheating, but at this moment my CPU is idling at 8 degrees C
  Using a different sound card
  Trying every different realtek driver I can find

The only other thing I can think of that may be causing this is that I have recently upgraded my PC, installing a new motherboard, SSD and Windows 8.1. I will try my old motherboard again, and I may try a new install of Windows 8.1 within the next few days, but both are pretty time consuming.

Does anyone have any other ideas about what could be causing this or what kind of fixes might help?

Specs:
Windows 8.1
AMD FX-4170
MSI 970 Motherboard
8GB Crucial RAM
XFX AMD Radeon R9 280
Crucial MX100 256GB SSD, 2x Seagate 1TB HDD, 1x Western Digital 500GB HDD

 

[Nine Layer Nige]

Mine also does this lockup and infinite sound loop sometimes. It requires a mains switch off for me. Not often and only when playing games (most on BF4). It only does it to mine when my pc gets too hot, well thats what I put it down to.

 

[carlwaterman]

I've completely run out of ideas now.

Since last week I've sent that MSI board back and reinstalled my old board, which works fine, no crashes at all.
I ordered a new board, a Gigabyte 990XA-UD3, which arrived last night. I installed that and installed a clean install of windows and still get this crash.

Obviously this is a motherboard issue, but what could be causing it over two different motherboards and a clean install of windows?