I suspect not. In many cases the only difference is the chip is mounted to the motherboard and connected via a internal pcie connection. Many times the actual wifi chips are the same.
Most problems with wifi in desktops are that the antenna is located so close to the back of the case. They make short antenna cable to extend the antenna away to the top of the case.
Mu-mimo is hard to say how much benefit you really see. You can setup lab test results that show some small ability to keep different user traffic separate but in real world installs it is not so easy to see if you actually get any benefit. The largest issue with wifi is not the other machines on your network it is the machines in your neighbors house...