The Crossload 1 test, in the TechPowerUp.com reviews of the EVGA SuperNOVA NEX750G and Thermaltake Toughpower XT Platinum 1275 W, places a heavy load on the minor (+3.3V and +5V) rails and a light load (~ 2 Amps) on the +12V rail.
TechPowerUp.com has since modified their Crossload 1 test to match the testing methodology that Intel uses for Haswell Ready (a.k.a. C6/C7 processor power state) testing (i.e. 0 ~ 0.1 Amps on the +12V rail).
It's almost impossible for PSUs that use a group regulated circuit design to pass this test without one or more of the rails going out of ATX12V specs. When one or more rail goes out of spec it may trigger one of the PSU's protection circuits causing the PSU to shut itself down.
Any PSU that claims to be Intel Haswell Ready without being able to pass the test, according to Intel's testing methodology, is lying.
On a good PSU no rail should ever go out of spec no matter how it's loaded since it could lead to damaged components.
The +5V rail is used to power some semi-conductor chips on the motherboard, SSDs, hard disk drives, optical drives, some powered USB devices, ..., etc.