Hi, I'm Jewel with Kingston Technical Support. The HyperX Fury memory is our newest line of HyperX memory and it is plug and play, meaning it will run at it's advertised speed or the highest the system supports when plugged in without making changes in BIOS. Without the exact part numbers I cannot really say if there are any differences between the two sets of memory. Generally speaking, the differences between the different lines of HyperX memory are the way it looks and the range of speeds/capacity that it is available. If the memory you are looking at has the same capacity, speed and timing settings there would be essentially no difference in performance. For any further assistance, please call us at 1-800-435-0640 (USA and Canada...