not using which cable? Your message is a bit "blurry" if i can say so.
Though you should always have both the 6-pin and 8-pin connected in the gpu, not plugging both in would mean the gpu doesn't get enough power.
Your psu having two of each cable is just because it's capacity is big enough to fit two gpus of a med/high-end power range for a CF/SLI setup. Though i would at max get two R9 280X's, not two R9 290's for a 750w psu.