Question Radeon RX 480 not working in new motherboard

Motherboard: Asus Prime b450 plus
GPU: XFX Radeon RX 480
CPU: Ryzen 5 5600
PSU: Corsair TX650M, 650W PSU
A Samsung 1tb SSD

That's what I remember off the top of my head.
Did this rig work with a previous GPU? Your motherboard requires a BIOS update (3211 or newer) to use the 5000 series CPU.

https://www.asus.com/motherboards-c...plus/helpdesk_cpu/?model2Name=PRIME-B450-PLUS

https://www.asus.com/motherboards-c...lus/helpdesk_bios/?model2Name=PRIME-B450-PLUS
 
The old FX is of no use. Connecting directly to the motherboard video headers won't work as the CPU lacks an integrated GPU (only those models ending in G have those).

You need a compatible CPU installed in your motherboard in order to update the BIOS for the 5600 to work.

From where did you purchase the motherboard?