Probably not unless you fancy reprogramming the firmware in the drives, assuming this is even possible or sensible. Leave them as they are.
Provided the drives can be tested and shown to work normally, I wouldn't be too worried about mixing a bunch of drives with different part numbers on a home NAS.
SFF8643 is a merely a connector type. Presumably it's the one fitted to your Adaptec card. My LSI cards use a different connector type SFF8087. They may be the same electrically, but obviously they're not physically compatible. If you buy a different controller card and it has SFF8087, you'll need to buy new leads.
This Reddit post implies there may be an HBA (Host Bus Adapter) option for the ASR-7160S. If you do some on-line research, you might be able to find some firmware to reflash the card from RAID to HBA, but you could end up "bricking" the card. Flashing cards can be simple or very difficult.
https://www.reddit.com/r/homelab/comments/oaf65e/adaptec_asr71605_any_good/
Some HP RAID controllers have a "pass-through" option, which can be invoked by running special (hard to find) software on a proprietary (HP) DVD. Switching the card's firmware from RAID to HBA makes it similar to IT-mode.
The net result is I switched a built-in HP RAID controller over to HBA which made it possible to run a ZFS operating system, but pkease note HP's HBA is not true IT-mode. The purists would argue I should have reflashed the card to IT-mode or fitted an LSI card. There might be a similar option to disable RAID on your Adaptec card.
Getting back to your problem, I think the easiest solution is to buy a "proper" LSI IT-mode card so you could check your "suspect" drives. I'd stick with SAS2 controllers (6Gb/s) although you probably wouldn't notice any difference with an older SAS1 card (3Gb/s). SAS3 (12GB/s) would be a waste of money with 2TB hard disks but would come into its own with faster SSD arrays.
This card on eBay appears to be a genuine LSI 9207-8i (second hand OEM) card. Consider also 9211-8i. I've no idea if you live in the US, Europe, Australia or Inner Mongolia, but you could do worse than check your local eBay or equivalent. The thing to note is where it says "IT mode, ZFS, FreeNAS, unRAID". Don't buy the version (9207-8e?) with RAID firmware.
https://www.ebay.com/itm/143375090253?_skw=lsi+sas+9211-8i&itmmeta=01JMSAYK1VN4PCV60GB7WRY171&hash=item2161d2424d:g:f2EAAOSwIuNhlfE1&itmprp=enc:AQAKAAAA0FkggFvd1GGDu0w3yXCmi1dmtUlMz/FnFHPm/MdwlgcmhA+sKR8PFv1GC51U9oggLiRt7IcEapb87hSzLYHk2h05sv/p3gCbK3wVwHoRL6pLojkia8DtFzn5vxBAFL6Pjqyy20HEliVnsjb8X/d2naGfFkoXXH8Onubx3CBGboSf3sBDC2KwMBCQtDWF9Y8cYXa2WB+KzYMGTXt2NaD/5lfUHPqCL4u9oXV+44UPjuVgzOCYKzwZEFItwR4/REqGfB4nkXfFFWFyWEwygidGOWg=|tkp:BlBMUIqx-qqmZQ
If your SAS drives have a contiguous data/power connector like the ST2000NM0001 shown below, you won't be able to fit any of the commonly available SFF8087 to quad SATA cables bundled with many cards. They're intended for people using ordinary SATA drives with a SAS card.
What you need instead is something like this where you can plug a standard SATA power connector into the rear of each SAS adapter:-
https://www.amazon.co.uk/YIWENTEC-SFF-8087-SFF-8482-Connectors-Power/dp/B07MXWB6S2?th=1