You should use RAID to merge the drives because typically video editors have two sets of data to manage:
- your actual video clips
- pre/post-process temporary files
Both of these can be huge, and it can be messy to try and manage the size of one drive or the other so that the program doesn't run out of room for your movies or its temp files.
RAID makes many drives (up to seven or more with some RAID controllers) appear as one huge volume so there's no need to manage free space across multiple drives. The OS and editing program treat the drives as a single huge volume and your space management becomes very easy. Both your video clips and the temporary files just automatically spread across all drives in the RAID set.
If you have two identical-sized drives you will get a bit of a speed benefit by using striping rather than spanning/JBOD.
Striping shuffles data evenly across both drives in very small pieces or "stripes". If you need lots of data to move very quickly, striping overcomes the read/write delays of a single drive.
Drive Spanning or JBOD simply stacks the drive space like a stack of encyclopedias, and they don't need to all be the same size. Data is written to one drive until full, then then continues writing onto the next drive, and the next, and so forth. But since the 2nd drive is not even used until the first is full, your overall read/write throughput may be only about half the speed of striping.
Note that striping/spanning give NO data protection. If any one drive of the array fails you will very likely lose ALL the data in the stripe/span set.