1) Probably a shielding issue, causing corruption to the analog output of the sound.
2) It can also be insufficient process scheduling for the audio driver. You can verify with LatencyMON->
http://www.resplendence.com/latencymon
Issues with scheduling show up like "chirps", but interference physically is different. For example, moving your mouse around may alter the sound and be noticeable in headphones.
3) Solutions?
If LatencyMON reveals no issues, and it's not the speakers themselves since headphones don't help, it's probably only these things that can help:
a) Unhook all HDD/SSD or other components not necessary to boot up. As well as mouse and keyboard when the sound is going (if they interfere it should go away).
b) Reinstall Windows and/or try a Linux distro. Linux:
- download and burn Linux Mint 64-bit to a USB stick (4GB or higher)
- shut down and unhook all drives (HDD, SSD, DVD)
- change audio settings if necessary (may not work with certain sound cards)
- test
- if you have no problems you have narrowed it down to either a SOFTWARE issue, or one of your drives creating interference
c) SOUND CARD or external DAC.
An external DAC takes the digital output from the computer (i.e. OPTICAL connection) and converts it into an analog signal for speakers or headphones. It can't have the analog signal corrupted so if that is the issue it will go away.
A better sound card may fix it, reduce it, or not help enough. It's still connected so prone to interference.
*Choosing an external DAC is complicated. There are:
a) Standalone DAC's which are small (and may only have one output)
b) DAC included in desktop speakers (in which case make sure it has a HEADPHONE output)