Gtx1060 can pull @ 120w. Cpu is anywhere from 50-100w, rest of the pc is anywhere from 50-100w on average. So that's @220w to 320w on the 12v rail. With that psu, you'd need to be on the short side for sure, with absolutely no OC whatsoever on either cpu or gpu. If the cpu is an i7 or fx 8 series in a decent sized pc, I'd stick with a gtx1050ti with no additional power connections, if it's an i3 or locked i5 or other low power needs cpu in a basic pc, the 1060 will work. Forget amd gpus, you can add another 50-100w on that figure to get similar performance.