It will depends, If u just migrating old OS to SSD using migration apps then it will work..
u just need change the OS partition on SSD to C: (or same as your old OS drive), then change/remove the Old OS partition (Old C: ) to something else
If u do clean install OS (recommended) then some will and some will not..
if the game depends on registry or have config files saved on C: (OS drive) or my doc, etc... it require reinstall..
If it stand alone type of game then it will work....