I was about to write "no", but I wanted to make sure and grabbed a 790 out of my pile, and compared board dimensions and screw hole placements with the ATX specifications. Standard micro ATX boards are 244mmx244mm (9.6"x9.6"). The actual Dell board size is 203mmx263mm. The hole placement seem to match but then I can't be sure... the imperial to metric conversion and screwing up with me. Even if holes would somewhat match, the connectors for front panels definitively don't match; Dell uses proprietary connectors. You could venture into pulling out each wires from Dell's connectors and try to fish them in a standard connector, but I wouldn't know where to begin. The power connectors seem standard; 24pin and 4pin for CPU. Newer motherboards need a 8pin CPU power connection though (thinking the 990 is newer and might have the 8pin? Not sure). And lastly, the rear I/O window seems the same size, but it is not removable on the Dell chassis. You would have to cut through the steel.