Hey,
I am having a similar problem. I also recently bought a Kone XTD from roccat and in the beginning everything seamed to be working fine. I downloaded the drivers setup a profile and saved it to the mouse, the profile worked and I was happy with it because it suited all the games pretty well. However as I got battlefield 4 I encountered 2 problems, the first one being that there was a delay between me pressing the button on my mouse and my game reacting and most of the time I had to press it 4 to 5 times for it to react at all (this does not happen in any other game) The second issue was or still is, that i needed a new keybinding setup for bf4 since when i created the other one it was mostly for simple fps games. This is why I went into the editor created a profile and klicked apply to set the profile to my mouse, however even after making new profiles and trying to load them onto the mouse, reseting everything in the drivers to default, updating and even reinstalling the drivers, the mouse continues to keep the first profile I ever loaded onto it. It is really starting to annoy me and I hope someone has a solution for this and your problem.