If you run a game like the original Crysis 1 in 8K or 12K max settings, the bigger issue will be the bottleneck from using PCIe 2.0. Really cannot say it will always be a CPU bottleneck when increasing the resolution alleviates the burden from the CPU.
Such old PC the bottleneck will not only be PCIE bus.
- DDR2 RAM to get 8GB or more can be very difficulty.
For modern OS like Win 10 you need at least 16GB
- SATA 2 SSD won't be running at full speed
- PCIE Bus 2.0
- Legacy/CSM mode May not be able to boot if the GPU has no legacy VBIOS.
Certain card will have a GPU BIOS screen when you boot only these type of
GPU will work on older motherboards.
Even if you can make it work, the performance will be very bad especially once OS take up
more than 8GB that's it. To get 16GB DDR2 if you can find one that will be a history in the making.
I still have a old AMD Phenom II rig unfornuately I have to retired it.
Mainly due to RAM as even with Win 7 when it hits more than 4GB the performance will suffer.
Is diffiicult to get 8GB RAM and once I tried it but it kept crashing so I retire it.