I am currently running both a 980 and 770 at the same time, not in SLI though of course. I have the 980 in the primary slot and set to be the phys-x device. The 770 in the second slot is where I have my 2nd monitor plugged in. Is there any actual benefit to this? I left the 770 in after getting the 980 as a means to run my 2nd (sometimes 3rd) monitor. I don't actually play games across multiple monitors, but use them for Teamspeake and Chrome (or w/e else) monitoring while I have a game open.