Do not do both "Auto OC" and change settings manually. In fact, I wouldn't use any BIOS "auto oc" settings.
Just enable PBO in advanced mode and then make an all-core curver optimizer setting of -10 or -12 maximum to start. Then use an additional boost clock of +50Mhz or so. You can push it further with +200 but it will probably hurt performance as it heats up the cores faster so the algorithm pulls clocks sooner and further. The same is true of Scalar setting: don't go very high, 2x preferred 6x or 7x max, for that for the same reason.
Tweaking in good per-core CO settings is time consuming and needs a lot of testing for stability.