There are two different ways to have multiple GPUs. You can have them render as a team (e.g. SLI, Crossfire), which increases performance by using both processors. However, both cards need the same contents in the VRAM, so 2x 2GiB cards still act as 2GiB.
Or you can have them separate, which allows you to have large numbers of displays. You can use the full VRAM for each card, but won't get the increased performance.