Bottlenecking in the sense that you're probably describing is the limits of a CPU that are imposed on a graphics card. Bottlenecking occurs in games that are "CPU-bound" which means that they need a higher ratio of CPU resources to GPU resources. Games like Skyrim, Battlefield 3 and Civilization V fall into this category. The frame rate of the game will be imposed by the speed of the CPU instead of the speed of the GPU. Most games are "GPU-bound" which means that although a certain speed of CPU is needed, the speed of the GPU is far more crucial. In a CPU-bound game, the CPU will dictate the frame rate no matter what kind of card in installed. For instance, if you have a Core2Duo in Battlefield 3, you will get the same frame rate with a Radeon HD 7770 that you will with a Radeon HD 7970. It's because the CPU is limiting the framerates to what it can handle, no matter what the GPU is capable of. The bottleneck will be larger on a higher-end card because the actual frame rate will be further from its theoretical maximum frame rate on that game than on a lower-end card. The idea that a weaker CPU cannot "handle" a high-end card is absurd. If it couldn't, Windows wouldn't load at all. In truth, the weaker CPU cannot handle certain games. The GPU involved is irrelevant.
The FX-4130 would most likely work just fine with a Radeon HD 7750.