I have a b450 tomahawk motherboard. To start off I know that when i have the m.2 plugged in it will disable 2 sata ports. My ssd is not plugged into those sata ports. I have a harddrive plugged in which works fine with the m.2 plugged in. So i tried swapping the sata cable with my hdd to my ssd and it still doesn't work. When I plug out my m.2 it works fine.