2 different form factors, an ATX (the MSI) vs the micro GB -while both actually can run 1600 DRAM (that's based on the chipset, either can run lower, not that anyone would want to), the MSI will have a few extras just from the form factor, both have a PCI-E 3 slot (x16), both have a PCI-E 2 slot (x4) the GB has better user ratings at the Egg, but big difference is the form factor, will your case take either? What CPU are you planning to run