If they are DOS programs, they will run within DOSBOX.
http://www.dosbox.com/
If they are just older 16 bit games like skifree and samegame, Then a VM may be your best bet. Within a VM you can install another operating system like Windows XP. Please note VM's do not perform as well as having the system it self.
Some older games, had 16 bit installers that do not work even with the game being 32 bit, some can be extraced by winrar or similar, but not all.