It'll run perfectly.
FYI my new rig (in avatar) runs my 'old' and much abused HD7950 flawlessly.
Few points.
Once the build is up and running, consider checking for BIOS updates, but don't install one unless there is problems.
Good as it is the GTX680 is getting 'old', if you don't already, keep an eye on graphics card developments through tech sites, you'll be well informed when the time comes to upgrade.
Get a MB which has an integrated graphics output, they're really handy for troubleshooting.
Don't go cheap on the power supply, quality is more important than claimed output.
Even if you're going to stick to stock speed, adding a inexpensive CPU cooler like the Coolermaster Hyper 212 Evo into the mix is a good investment, it'll be...